Landscape of circulating diagnostic biomarkers in pancreatic malignancies
نویسندگان
چکیده
منابع مشابه
Circulating microRNAs as diagnostic biomarkers for cardiovascular
37 One of the major challenges in cardiovascular disease is the identification of reliable clinical 38 biomarkers which can be measured routinely in plasma. MicroRNAs were recently 39 discovered to circulate in the bloodstream in a remarkably stable form. Because of their 40 stability and often tissueand disease-specific expression, and the possibility to measure 41 them with high sensitivity a...
متن کاملCirculating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers
Effective management of breast cancer depends on early diagnosis and proper monitoring of patients' response to therapy. However, these goals are difficult to achieve because of the lack of sensitive and specific biomarkers for early detection and for disease monitoring. Accumulating evidence in the past several years has highlighted the potential use of peripheral blood circulating nucleic aci...
متن کاملCirculating microRNAs in Pancreatic Juice as Candidate Biomarkers of Pancreatic Cancer
Development of sensitive and specific biomarkers, preferably those circulating in body fluids is critical for early diagnosis of cancer. This study performed profiling of microRNAs (miRNAs) in exocrine pancreatic secretions (pancreatic juice) by microarray analysis utilizing pancreatic juice from 6 pancreatic ductal adenocarcinoma (PDAC) patients and two pooled samples from 6 non-pancreatic, no...
متن کاملNovel Diagnostic and Predictive Biomarkers in Pancreatic Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease for a multitude of reasons including very late diagnosis. This in part is due to the lack of understanding of the biological behavior of PDAC and the ineffective screening for this disease. Significant efforts have been dedicated to finding the appropriate serum and imaging biomarkers to help early detection and predict response...
متن کامل[Circulating Serum MicroRNA as Diagnostic Biomarkers for Multiple Myeloma].
OBJECTIVE To investigate the diagnostic value of circulating serum miRNA for multiple myeloma. METHODS Forty blood samples from patients with multiple myeloma were collected from July 2013 to June 2014 in Department of Hematology, Zhongshan Hospital Affiliated to Xiamen University. The real-time quantitative PCR was performed to detect the serum expression levels of miRNAs (miR-29a, miR-155, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Pancreatic Cancer
سال: 2020
ISSN: 2616-2741
DOI: 10.21037/apc.2020.03.04